Onasemnogene Abeparvovec (ZOLGENSMA) – Uses, Dosage & Brands in UAE

About Onasemnogene Abeparvovec

Class:|Gene therapy product Use:|Treatment of spinal muscular atrophy (SMA) in pediatric patients less than 2 years of age with bi-allelic mutations in the SMN1 gene Adult dose:|Not applicable Pediatric dose:|1.1 x 10^14 vector genomes per kg of body weight, administered as a single-dose intravenous infusion Side effects:|Elevated liver enzymes, vomiting, thrombocytopenia, increased troponin-I, fever, decreased appetite Contraindications:|Hypersensitivity to Onasemnogene Abeparvovec or

Drug Class

|Gene therapy product

Uses & Indications

|Treatment of spinal muscular atrophy (SMA) in pediatric patients less than 2 years of age with bi-allelic mutations in the SMN1 gene

Storage Requirements

|Store frozen at -60°C to -90°C; thaw and use immediately or store refrigerated

Manufacturer & Packaging

Manufacturer: Novartis Gene Therapies EU Limited[Dublin;Ireland], Ireland

Package Size

1 Kit (5.5 ml or 8.3 ml Single use Vial x 2 to 14)

Price & Supplier

Price in UAE: AED 7340000.00

Dosage Information

Adult Dose

|Not applicable

Pediatric Dose

|1.1 x 10^14 vector genomes per kg of body weight, administered as a single-dose intravenous infusion

Side Effects

|Elevated liver enzymes, vomiting, thrombocytopenia, increased troponin-I, fever, decreased appetite

Other Brands & Strengths Available in UAE

Different brands and strengths of Onasemnogene Abeparvovec available in UAE pharmacies:

ZOLGENSMA 2 x 10^13 vector genomes/mL Solution For Infusion ZOLGENSMA 2 x 10^13 vector genomes/mL Solution For Infusion

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

Onasemnogene Abeparvovec – Uses, Dosage, and Brands in UAE