About Osilodrostat Phosphate
Class: | Cortisol synthesis inhibitor
Use: | Treatment of Cushing's disease in adults who are not candidates for surgery or for whom surgery has failed
Adult dose: | Initial dose of 2 mg orally once daily; may be increased based on clinical response and tolerability, with a maximum dose of 30 mg per day
Pediatric dose: | Safety and efficacy have not been established in pediatric patients
Side effects: | Adrenal insufficiency, headache, fatigue, nausea, diarrhea, hypertension, hypokalemia
Drug Class
Cortisol synthesis inhibitor
Uses & Indications
Treatment of Cushing's disease in adults who are not candidates for surgery or for whom surgery has failed
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light and moisture
Manufacturer & Packaging
Manufacturer: RECORDATI RARE DISEASES[PUTEAUX;France], France
Package Size
60’s[10's Blister x 6]
Price & Supplier
Price in UAE: AED 7552.50
Dosage Information
Adult Dose
Initial dose of 2 mg orally once daily; may be increased based on clinical response and tolerability, with a maximum dose of 30 mg per day
Pediatric Dose
Safety and efficacy have not been established in pediatric patients
Side Effects
Adrenal insufficiency, headache, fatigue, nausea, diarrhea, hypertension, hypokalemia, and increased liver enzymes
Contraindications & Precautions
Hypersensitivity to osilodrostat or any component of the formulation; adrenal insufficiency; concurrent use of strong CYP3A4 inhibitors
Important Warnings
Risk of adrenal insufficiency; monitor for signs and symptoms; may cause serious liver injury; caution in patients with a history of liver disease or those taking medications that affect liver function
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.