Pegloticase (KRYSTEXXA) – Uses, Dosage & Brands in UAE

About Pegloticase

Class: | Uric acid lowering agent, enzyme replacement therapy Use: | Treatment of chronic gout in adult patients who have not responded adequately to conventional therapy Adult dose: | 8 mg administered as an intravenous infusion every 2 weeks Pediatric dose: | Not established; not indicated for use in pediatric patients Side effects: | Infusion reactions (e.g., nausea, vomiting, fever, chills), gout flares, headache, fatigue, and potential for anaphylaxis Contraindications: | Known hy

Drug Class

Uric acid lowering agent, enzyme replacement therapy

Uses & Indications

Treatment of chronic gout in adult patients who have not responded adequately to conventional therapy

Storage Requirements

Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light

Manufacturer & Packaging

Manufacturer: Horizon Therapeutics USA Inc., United States of America

Package Size

1 Vial

Price & Supplier

Price in UAE: AED 96014.00

Dosage Information

Adult Dose

8 mg administered as an intravenous infusion every 2 weeks

Pediatric Dose

Not established; not indicated for use in pediatric patients

Side Effects

Infusion reactions (e.g., nausea, vomiting, fever, chills), gout flares, headache, fatigue, and potential for anaphylaxis

Important Warnings

Risk of serious allergic reactions, including anaphylaxis; monitor patients for infusion reactions; may precipitate gout flares during initial treatment; G6PD deficiency may lead to hemolytic anemia.

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

Pegloticase – Uses, Dosage, and Brands in UAE