Pegylated liposomal Irinotecan (ONIVYDE) – Uses, Dosage & Brands in UAE

About Pegylated liposomal Irinotecan

Class: | Antineoplastic agent, Topoisomerase I inhibitor, Pegylated liposomal formulation Use: | Treatment of metastatic pancreatic adenocarcinoma in combination with fluorouracil and leucovorin in patients who have previously received gemcitabine-based therapy Adult dose: | 70 mg/m² administered as an intravenous infusion over 90 minutes every two weeks Pediatric dose: | Safety and efficacy have not been established in pediatric patients; not recommended for use in this population Side

Drug Class

Antineoplastic agent, Topoisomerase I inhibitor, Pegylated liposomal formulation

Uses & Indications

Treatment of metastatic pancreatic adenocarcinoma in combination with fluorouracil and leucovorin in patients who have previously received gemcitabine-based therapy

Storage Requirements

Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; once diluted, use immediately or store for a maximum of 24 hours at 2°C to 8°C

Manufacturer & Packaging

Manufacturer: Les Laboratoires Servier, France

Package Size

10ml Vial

Price & Supplier

Price in UAE: AED 5090.97

Dosage Information

Adult Dose

70 mg/m² administered as an intravenous infusion over 90 minutes every two weeks

Pediatric Dose

Safety and efficacy have not been established in pediatric patients; not recommended for use in this population

Side Effects

Nausea, vomiting, diarrhea, fatigue, abdominal pain, neutropenia, anemia, thrombocytopenia, elevated liver enzymes

Important Warnings

Risk of severe diarrhea, myelosuppression, and infusion-related reactions; monitor for signs of dehydration and consider prophylactic antiemetics; caution in patients with hepatic impairment

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

Pegylated liposomal Irinotecan – Uses, Dosage, and Brands in UAE