About Pegzilarginase
Class: | Enzyme replacement therapy (specifically, a recombinant human arginase)
Use: | Treatment of arginase deficiency, a rare genetic disorder leading to hyperargininemia
Adult dose: | 5 mg/ml administered as an intravenous or subcutaneous infusion, typically dosed based on body weight and clinical response
Pediatric dose: | Dosing is individualized based on weight; generally, the same concentration is used as in adults, with careful monitoring
Side effects: | Common side effects incl
Drug Class
Enzyme replacement therapy (specifically, a recombinant human arginase)
Uses & Indications
Treatment of arginase deficiency, a rare genetic disorder leading to hyperargininemia
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; once removed from the refrigerator, can be kept at room temperature for up to 24 hours
Manufacturer & Packaging
Manufacturer: Immedica Pharma AB, Sweden
Package Size
0.4ml Vial
Price & Supplier
Price in UAE: AED 21366.00
Dosage Information
Adult Dose
5 mg/ml administered as an intravenous or subcutaneous infusion, typically dosed based on body weight and clinical response
Pediatric Dose
Dosing is individualized based on weight; generally, the same concentration is used as in adults, with careful monitoring
Side Effects
Common side effects include injection site reactions, headache, nausea, vomiting, diarrhea, and fatigue
Contraindications & Precautions
Hypersensitivity to pegzilarginase or any of its components; caution in patients with a history of severe allergic reactions
Important Warnings
Risk of hypersensitivity reactions; monitor for signs of anaphylaxis; patients should be advised to report any unusual symptoms immediately; not recommended for use in patients with severe liver dysfunction
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.