About pemigatinib
Class: | Kinase inhibitor
Use: | Treatment of adults with locally advanced or metastatic cholangiocarcinoma with a fibroblast growth factor receptor 2 (FGFR2) fusion or other rearrangement
Adult dose: | 13.5 mg orally once daily for 14 days followed by 7 days off (28-day cycle); dose may be adjusted based on tolerability
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Fatigue, hyperphosphatemia, diarrhea, nausea, stomatitis, and decreased appet
Drug Class
Kinase inhibitor
Uses & Indications
Treatment of adults with locally advanced or metastatic cholangiocarcinoma with a fibroblast growth factor receptor 2 (FGFR2) fusion or other rearrangement
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture
Manufacturer & Packaging
Manufacturer: Incyte Biosciences International Sàrl [1110Morges;Switzerland], Switzerland
Package Size
14's (14's Blister x 1)
Price & Supplier
Price in UAE: AED 39507.00
Dosage Information
Adult Dose
13.5 mg orally once daily for 14 days followed by 7 days off (28-day cycle); dose may be adjusted based on tolerability
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Fatigue, hyperphosphatemia, diarrhea, nausea, stomatitis, and decreased appetite
Contraindications & Precautions
Hypersensitivity to pemigatinib or any component of the formulation; severe renal impairment (CrCl <30 mL/min)
Important Warnings
Risk of ocular toxicity (including retinal detachment), hyperphosphatemia, and hepatotoxicity; monitor for signs and symptoms of these conditions; avoid use in pregnancy due to potential fetal harm
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.