About Perampanel
Class: | Anticonvulsant, AMPA receptor antagonist
Use: | Adjunctive treatment of partial-onset seizures in patients with epilepsy aged 12 years and older; also indicated for primary generalized tonic-clonic seizures in patients aged 12 years and older.
Adult dose: | Initial dose: 2 mg orally once daily; may be increased to 4 mg after 1 week based on tolerability and efficacy; maximum dose: 12 mg/day.
Pediatric dose: | For patients aged 12 years and older: Initial dose: 2 mg orally once dai
Drug Class
Anticonvulsant, AMPA receptor antagonist
Uses & Indications
Adjunctive treatment of partial-onset seizures in patients with epilepsy aged 12 years and older; also indicated for primary generalized tonic-clonic seizures in patients aged 12 years and older.
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light.
Manufacturer & Packaging
Manufacturer: Eisai Europe Limited, UNITED KINGDOM
Package Size
28's (14's Blister x 2)
Price & Supplier
Price in UAE: AED 662.50
Dosage Information
Adult Dose
Initial dose: 2 mg orally once daily; may be increased to 4 mg after 1 week based on tolerability and efficacy; maximum dose: 12 mg/day.
Pediatric Dose
For patients aged 12 years and older: Initial dose: 2 mg orally once daily; may be increased to 4 mg after 1 week; maximum dose: 12 mg/day. For children aged 2 to <12 years, dosing is weight-based and should be adjusted accordingly.
Side Effects
Dizziness, drowsiness, fatigue, irritability, weight gain, and ataxia; may also cause mood changes, including aggression and suicidal thoughts.
Contraindications & Precautions
Hypersensitivity to perampanel or any component of the formulation; caution in patients with a history of psychiatric disorders.
Important Warnings
Risk of serious neuropsychiatric events, including aggression, hostility, irritability, and suicidal ideation; monitor for changes in mood or behavior; not recommended for use in patients with a history of substance use disorder.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.