About Pioglitazone Hydrochloride,Metformin Hydrochloride
Class: | Antidiabetic agent (Thiazolidinedione and Biguanide combination)
Use: | Management of type 2 diabetes mellitus in adults, particularly in patients who are not adequately controlled on metformin alone or who require dual therapy.
Adult dose: | Pioglitazone 15 mg and Metformin 850 mg taken orally once daily, with adjustments based on blood glucose levels and tolerability.
Pediatric dose: | Safety and efficacy not established for pediatric patients under 18 years; not recommended.
Drug Class
Antidiabetic agent (Thiazolidinedione and Biguanide combination)
Uses & Indications
Management of type 2 diabetes mellitus in adults, particularly in patients who are not adequately controlled on metformin alone or who require dual therapy.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, away from moisture and light.
Manufacturer & Packaging
Manufacturer: Tabuk Pharmaceutical Manufacturing Co., SAUDI ARABIA
Package Size
60's HDPE Bottle
Price & Supplier
Price in UAE: AED 80.00
Dosage Information
Adult Dose
Pioglitazone 15 mg and Metformin 850 mg taken orally once daily, with adjustments based on blood glucose levels and tolerability.
Pediatric Dose
Safety and efficacy not established for pediatric patients under 18 years; not recommended.
Side Effects
Common side effects include headache, dizziness, weight gain, edema, gastrointestinal disturbances (nausea, diarrhea), and increased risk of heart failure.
Contraindications & Precautions
Contraindicated in patients with a history of hypersensitivity to either drug, severe renal impairment (eGFR < 30 mL/min), active liver disease, or heart failure.
Important Warnings
Increased risk of lactic acidosis, particularly in patients with renal impairment, dehydration, or other conditions predisposing to hypoxia; monitor renal function regularly. Risk of heart failure with pioglitazone; assess for signs and symptoms.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.