About Pralatrexate
Class: | Antimetabolite, Folate Analog
Use: | Treatment of peripheral T-cell lymphoma (PTCL) in patients who have received at least one prior therapy
Adult dose: | 30 mg/m² administered as an intravenous infusion over 3 hours once weekly for 6 weeks, followed by a 1-week rest period; may be adjusted based on tolerance and response
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Nausea, vomiting, fatigue, mucositis, myelosuppression (including a
Drug Class
Antimetabolite, Folate Analog
Uses & Indications
Treatment of peripheral T-cell lymphoma (PTCL) in patients who have received at least one prior therapy
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: Mundipharma Medical Company, SWITZERLAND
Package Size
1 Ampoule
Price & Supplier
Price in UAE: AED 18076.50
Dosage Information
Adult Dose
30 mg/m² administered as an intravenous infusion over 3 hours once weekly for 6 weeks, followed by a 1-week rest period; may be adjusted based on tolerance and response
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Nausea, vomiting, fatigue, mucositis, myelosuppression (including anemia, neutropenia, thrombocytopenia), rash
Contraindications & Precautions
Hypersensitivity to pralatrexate or any component of the formulation; pregnancy; breastfeeding
Important Warnings
Risk of severe myelosuppression; monitor blood counts; potential for serious infections; avoid use in patients with renal impairment; use caution in patients with liver impairment; teratogenic effects; ensure adequate hydration and folate supplementation prior to treatment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.