About Rifampicin,Isoniazid
            
            Class: | Antitubercular agents  
Use: | Treatment of active tuberculosis (TB) in combination with other antitubercular medications; also used for latent TB infection.  
Adult dose: | RIFAMPICIN 300 mg and ISONIAZID 150 mg taken once daily, typically for 6 to 9 months, depending on the TB type and treatment regimen.  
Pediatric dose: | For children, the dosage is weight-based; typically, RIFAMPICIN is dosed at 10-20 mg/kg/day and ISONIAZID at 10 mg/kg/day, not exceeding adult doses.  
Side effect
         
        
            
                
                
                    
                        Drug Class
                    
                    Antitubercular agents
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of active tuberculosis (TB) in combination with other antitubercular medications; also used for latent TB infection.
                 
                
                
                    
                        Storage Requirements
                    
                    Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, protected from moisture and light.
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Sanofi, UNITED KINGDOM
                    
                    
                    Package Size
                    56's
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 219.52
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        RIFAMPICIN 300 mg and ISONIAZID 150 mg taken once daily, typically for 6 to 9 months, depending on the TB type and treatment regimen.
                    
                    
                        Pediatric Dose
                    
                    
                        For children, the dosage is weight-based; typically, RIFAMPICIN is dosed at 10-20 mg/kg/day and ISONIAZID at 10 mg/kg/day, not exceeding adult doses.
                    
                 
                
                
                    
                        Side Effects
                    
                    Common side effects include nausea, vomiting, abdominal pain, fatigue, headache, and liver enzyme elevation.
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Contraindicated in patients with a history of hypersensitivity to rifampicin or isoniazid, active liver disease, and acute liver injury.
         
        
        
            
                Important Warnings
            
            Monitor liver function tests regularly; risk of hepatotoxicity, especially in patients with pre-existing liver conditions or those taking other hepatotoxic drugs. Use with caution in patients with a history of alcohol abuse.
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.