About Rifampicin,Pyrazinamide,Ethambutol,Isoniazid
Class: | Antitubercular agents
Use: | Treatment of active tuberculosis (TB) in combination therapy
Adult dose: | Rifampicin 150 mg, Isoniazid 75 mg, Pyrazinamide 400 mg, Ethambutol 275 mg; typically administered as 4 tablets once daily
Pediatric dose: | Dosing varies by weight; generally, Rifampicin 10-20 mg/kg, Isoniazid 10-15 mg/kg, Pyrazinamide 25 mg/kg, Ethambutol 15 mg/kg, not exceeding adult doses
Side effects: | Hepatotoxicity, gastrointestinal disturbances, rash, fever, arthralgi
Drug Class
Antitubercular agents
Uses & Indications
Treatment of active tuberculosis (TB) in combination therapy
Storage Requirements
Store at room temperature (20-25°C), protect from moisture and light
Manufacturer & Packaging
Manufacturer: Lupin Limited, INDIA
Package Size
200's
Price & Supplier
Price in UAE: AED 517.50
Dosage Information
Adult Dose
Rifampicin 150 mg, Isoniazid 75 mg, Pyrazinamide 400 mg, Ethambutol 275 mg; typically administered as 4 tablets once daily
Pediatric Dose
Dosing varies by weight; generally, Rifampicin 10-20 mg/kg, Isoniazid 10-15 mg/kg, Pyrazinamide 25 mg/kg, Ethambutol 15 mg/kg, not exceeding adult doses
Side Effects
Hepatotoxicity, gastrointestinal disturbances, rash, fever, arthralgia, optic neuritis (Ethambutol), peripheral neuropathy (Isoniazid)
Contraindications & Precautions
Severe liver disease, hypersensitivity to any component, concurrent use with certain medications (e.g., protease inhibitors, certain anticoagulants)
Important Warnings
Monitor liver function tests; risk of hepatotoxicity increases with age and pre-existing liver conditions; peripheral neuropathy risk with Isoniazid; Ethambutol may cause vision changes; use caution in patients with renal impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.