About RISDIPLAM
Class: | Survival of motor neuron 2 (SMN2) splicing modifier
Use: | Treatment of spinal muscular atrophy (SMA) in patients 2 months of age and older
Adult dose: | Not applicable as dosing is based on age and weight, not specific to adults
Pediatric dose: | For patients 2 months to <2 years: 0.2 mg/kg once daily; for patients ≥2 years and weighing <20 kg: 0.25 mg/kg once daily; for patients ≥2 years and weighing ≥20 kg: 5 mg once daily
Side effects: | Common side effects include fever, di
Drug Class
Survival of motor neuron 2 (SMN2) splicing modifier
Uses & Indications
Treatment of spinal muscular atrophy (SMA) in patients 2 months of age and older
Storage Requirements
Store at 2°C to 8°C (36°F to 46°F) in the refrigerator; protect from light; after reconstitution, the solution should be used within 64 days
Manufacturer & Packaging
Manufacturer: F.Hoffmann - La Roche Ltd[Basel;Switzerland], Switzerland
Package Size
1 Amber Glass Bottle + 5 oral syringes (1 ml x 2 + 6 ml x 2 + 12 ml x 1)
Price & Supplier
Price in UAE: AED 50820.50
Dosage Information
Adult Dose
Not applicable as dosing is based on age and weight, not specific to adults
Pediatric Dose
For patients 2 months to <2 years: 0.2 mg/kg once daily; for patients ≥2 years and weighing <20 kg: 0.25 mg/kg once daily; for patients ≥2 years and weighing ≥20 kg: 5 mg once daily
Side Effects
Common side effects include fever, diarrhea, rash, and upper respiratory tract infections
Contraindications & Precautions
No known contraindications; however, caution in patients with hypersensitivity to any component of the formulation
Important Warnings
Monitor liver function tests before and during treatment; potential for embryofetal toxicity; not studied in patients with severe hepatic impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.