About Ruxolitinib Phosphate
Class: | Janus kinase (JAK) inhibitor
Use: | Treatment of intermediate or high-risk myelofibrosis, polycythemia vera in patients who have had an inadequate response to or are intolerant of hydroxyurea, and graft-versus-host disease (GVHD)
Adult dose: | Myelofibrosis: Starting dose is 15 mg orally twice daily; Polycythemia vera: Starting dose is 10 mg orally twice daily; Adjustments may be made based on clinical response and tolerance
Pediatric dose: | Safety and efficacy in pediatric patie
Drug Class
Janus kinase (JAK) inhibitor
Uses & Indications
Treatment of intermediate or high-risk myelofibrosis, polycythemia vera in patients who have had an inadequate response to or are intolerant of hydroxyurea, and graft-versus-host disease (GVHD)
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Novartis Pharma AG, SWITZERLAND
Package Size
56's (14's Blister x 4)
Price & Supplier
Price in UAE: AED 22805.50
Dosage Information
Adult Dose
Myelofibrosis: Starting dose is 15 mg orally twice daily; Polycythemia vera: Starting dose is 10 mg orally twice daily; Adjustments may be made based on clinical response and tolerance
Pediatric Dose
Safety and efficacy in pediatric patients have not been established; not recommended for use in children
Side Effects
Common side effects include anemia, thrombocytopenia, neutropenia, headache, dizziness, and increased liver enzymes
Contraindications & Precautions
Hypersensitivity to ruxolitinib or any component of the formulation; active serious infections
Important Warnings
Risk of serious infections, including tuberculosis; may cause malignancies; monitor blood counts regularly; avoid live vaccines during treatment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.