About setmelanotide
Class: | Melanocortin receptor agonist
Use: | Indicated for chronic weight management in patients with obesity due to specific genetic disorders, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome.
Adult dose: | Initial dose of 1 mg subcutaneously once daily, may be titrated up to a maximum of 3 mg daily based on clinical response and tolerability.
Pediatric dose: | For patients aged 6 years and older, initial dose of 1 mg subcutaneously once daily, with titration simila
Drug Class
Melanocortin receptor agonist
Uses & Indications
Indicated for chronic weight management in patients with obesity due to specific genetic disorders, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome.
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Once removed from the refrigerator, it can be stored at room temperature for up to 30 days.
Manufacturer & Packaging
Manufacturer: Rhythm Pharmaceuticals Netherlands B.V., United Kingdom
Package Size
multidose vial
Price & Supplier
Price in UAE: AED 15354.50
Dosage Information
Adult Dose
Initial dose of 1 mg subcutaneously once daily, may be titrated up to a maximum of 3 mg daily based on clinical response and tolerability.
Pediatric Dose
For patients aged 6 years and older, initial dose of 1 mg subcutaneously once daily, with titration similar to adults based on response and tolerability.
Side Effects
Common side effects include nausea, vomiting, headache, flushing, and injection site reactions.
Contraindications & Precautions
Contraindicated in patients with known hypersensitivity to setmelanotide or any of its components.
Important Warnings
Risk of increased pigmentation, including skin and mucosal hyperpigmentation. Monitor for signs of adrenal insufficiency. Use caution in patients with a history of melanoma or other skin cancers.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.