About Sitaxentan
Class: | Endothelin receptor antagonist
Use: | Treatment of pulmonary arterial hypertension (PAH) to improve exercise capacity and delay clinical worsening
Adult dose: | 100 mg orally once daily
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended for use in children
Side effects: | Headache, flushing, nausea, abdominal pain, peripheral edema, elevated liver enzymes
Contraindications: | Hypersensitivity to sitaxentan or any component of the formu
Drug Class
Endothelin receptor antagonist
Uses & Indications
Treatment of pulmonary arterial hypertension (PAH) to improve exercise capacity and delay clinical worsening
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, protected from moisture and light
Manufacturer & Packaging
Manufacturer: Encysive Pharmaceuticals, UNITED KINGDOM
Package Size
28's
Price & Supplier
Price in UAE: AED 20769.00
Dosage Information
Adult Dose
100 mg orally once daily
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in children
Side Effects
Headache, flushing, nausea, abdominal pain, peripheral edema, elevated liver enzymes
Contraindications & Precautions
Hypersensitivity to sitaxentan or any component of the formulation; severe hepatic impairment; concomitant use with strong CYP3A4 inhibitors
Important Warnings
Risk of hepatotoxicity; monitor liver function tests before and during treatment; may cause fetal harm; not recommended during pregnancy; potential for drug interactions with CYP3A4 substrates
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.