About Sodium Phenylbutyrate
Class: | Urea cycle disorder treatment, Anticonvulsant
Use: | Treatment of urea cycle disorders (UCDs) in patients who cannot effectively eliminate ammonia, and as an adjunctive therapy in certain types of seizures.
Adult dose: | 10 g (50 mL) administered intravenously over 90 minutes, with adjustments based on clinical response and ammonia levels.
Pediatric dose: | 5 g/m² (up to a maximum of 10 g) administered intravenously over 90 minutes, with adjustments based on clinical response and
Drug Class
Urea cycle disorder treatment, Anticonvulsant
Uses & Indications
Treatment of urea cycle disorders (UCDs) in patients who cannot effectively eliminate ammonia, and as an adjunctive therapy in certain types of seizures.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) and protect from light; do not freeze.
Manufacturer & Packaging
Manufacturer: Special Products Limited, UNITED KINGDOM
Package Size
10ml Ampoule
Price & Supplier
Price in UAE: AED 149.50
Dosage Information
Adult Dose
10 g (50 mL) administered intravenously over 90 minutes, with adjustments based on clinical response and ammonia levels.
Pediatric Dose
5 g/m² (up to a maximum of 10 g) administered intravenously over 90 minutes, with adjustments based on clinical response and ammonia levels.
Side Effects
Nausea, vomiting, diarrhea, abdominal pain, headache, fatigue, and potential infusion site reactions.
Contraindications & Precautions
Hypersensitivity to sodium phenylbutyrate or any component of the formulation; caution in patients with renal impairment.
Important Warnings
Risk of hyperammonemia if not dosed correctly; monitor ammonia levels regularly; may cause metabolic disturbances; use with caution in patients with liver dysfunction.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.