About Sotorasib
Class: | Antineoplastic agent, KRAS inhibitor
Use: | Treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with a KRAS G12C mutation as detected by an FDA-approved test
Adult dose: | 120 mg orally once daily until disease progression or unacceptable toxicity
Pediatric dose: | Safety and efficacy in pediatric patients have not been established; not recommended for use in pediatric populations
Side effects: | Diarrhea, nausea, fatigue, liver enz
Drug Class
Antineoplastic agent, KRAS inhibitor
Uses & Indications
Treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with a KRAS G12C mutation as detected by an FDA-approved test
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Amgen Inc., U.S.A
Package Size
240's HDPE Bottle
Price & Supplier
Price in UAE: AED 43867.00
Dosage Information
Adult Dose
120 mg orally once daily until disease progression or unacceptable toxicity
Pediatric Dose
Safety and efficacy in pediatric patients have not been established; not recommended for use in pediatric populations
Side Effects
Diarrhea, nausea, fatigue, liver enzyme elevations, decreased appetite, cough, and rash
Contraindications & Precautions
Hypersensitivity to sotorasib or any of its components; severe hepatic impairment (Child-Pugh Class C)
Important Warnings
Risk of hepatotoxicity; monitor liver function tests prior to and during treatment; potential for interstitial lung disease/pneumonitis; caution in patients with a history of liver disease or those taking concomitant medications that may affect liver function
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.