About Teplizumab
Class: | Monoclonal antibody (anti-CD3)
Use: | Indicated for delaying the onset of stage 3 type 1 diabetes in at-risk individuals
Adult dose: | 14 mg administered as a subcutaneous injection over 14 days (1.0 mg on day 1, increasing to 14 mg by day 14)
Pediatric dose: | Not established; safety and efficacy in pediatric patients have not been determined
Side effects: | Headache, nausea, vomiting, infusion-related reactions, rash, and lymphopenia
Contraindications: | History of serious h
Drug Class
Monoclonal antibody (anti-CD3)
Uses & Indications
Indicated for delaying the onset of stage 3 type 1 diabetes in at-risk individuals
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: Provention Bio, Inc (Bridgewater, United States of America), United States of America
Package Size
1's Single- Dose Vial (2ml)
Price & Supplier
Price in UAE: AED 54895.50
Dosage Information
Adult Dose
14 mg administered as a subcutaneous injection over 14 days (1.0 mg on day 1, increasing to 14 mg by day 14)
Pediatric Dose
Not established; safety and efficacy in pediatric patients have not been determined
Side Effects
Headache, nausea, vomiting, infusion-related reactions, rash, and lymphopenia
Contraindications & Precautions
History of serious hypersensitivity reactions to teplizumab or any component of the formulation; active infections
Important Warnings
Risk of serious infections, including opportunistic infections; monitor for signs of infection; may cause cytokine release syndrome; caution in patients with a history of seizures or those receiving immunosuppressive therapy
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.