About Tezacaftor 50mg Ivacaftor,Ivacaftor
Class: | Cystic fibrosis transmembrane conductance regulator (CFTR) modulators
Use: | Treatment of cystic fibrosis in patients aged 12 years and older with specific CFTR gene mutations
Adult dose: | Tezacaftor 50 mg/Ivacaftor 75 mg: One tablet taken orally twice daily, approximately 12 hours apart
Pediatric dose: | Not approved for use in patients under 12 years of age
Side effects: | Common side effects include headache, nausea, diarrhea, abdominal pain, and elevated liver enzymes
Con
Drug Class
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators
Uses & Indications
Treatment of cystic fibrosis in patients aged 12 years and older with specific CFTR gene mutations
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture
Manufacturer & Packaging
Manufacturer: Vertex Pharmaceuticals Inc, U.S.A
Package Size
56s
Price & Supplier
Price in UAE: AED 94539.20
Dosage Information
Adult Dose
Tezacaftor 50 mg/Ivacaftor 75 mg: One tablet taken orally twice daily, approximately 12 hours apart
Pediatric Dose
Not approved for use in patients under 12 years of age
Side Effects
Common side effects include headache, nausea, diarrhea, abdominal pain, and elevated liver enzymes
Contraindications & Precautions
Hypersensitivity to tezacaftor, ivacaftor, or any component of the formulation; caution in patients with liver impairment
Important Warnings
Risk of hepatotoxicity; monitor liver function tests before and during treatment; may cause respiratory events; not recommended for patients with certain CFTR mutations (e.g., F508del homozygous)
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.