About Tofacitinib (as citrate)
Class: | Janus kinase (JAK) inhibitor
Use: | Treatment of moderate to severe rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis in adults; also approved for atopic dermatitis in certain cases.
Adult dose: | 5 mg orally twice daily for rheumatoid arthritis and psoriatic arthritis; 10 mg orally twice daily for ulcerative colitis (for up to 8 weeks).
Pediatric dose: | Not established for rheumatoid arthritis; for ulcerative colitis, 10 mg twice daily for patients 2 years and ol
Drug Class
Janus kinase (JAK) inhibitor
Uses & Indications
Treatment of moderate to severe rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis in adults; also approved for atopic dermatitis in certain cases.
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light.
Manufacturer & Packaging
Manufacturer: Pfizer Pharmaceuticals L.L.C., U.S.A
Package Size
60's HDPE Bottle
Price & Supplier
Price in UAE: AED 5073.00
Dosage Information
Adult Dose
5 mg orally twice daily for rheumatoid arthritis and psoriatic arthritis; 10 mg orally twice daily for ulcerative colitis (for up to 8 weeks).
Pediatric Dose
Not established for rheumatoid arthritis; for ulcerative colitis, 10 mg twice daily for patients 2 years and older, with weight-based adjustments.
Side Effects
Common side effects include upper respiratory tract infections, headache, nausea, diarrhea, and increased liver enzymes.
Contraindications & Precautions
Hypersensitivity to tofacitinib or any component of the formulation; active infections, including tuberculosis; severe hepatic impairment.
Important Warnings
Risk of serious infections, malignancies, thrombosis, and gastrointestinal perforations; monitor for signs of infection and perform screening for tuberculosis prior to initiation.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.