About Trastuzumab (HERZUMA)
Class: | Monoclonal antibody (HER2/neu receptor antagonist)
Use: | Treatment of HER2-positive breast cancer (metastatic and adjuvant settings) and gastric cancer (HER2-positive)
Adult dose: | 8 mg/kg loading dose followed by 6 mg/kg every 3 weeks for metastatic breast cancer; for adjuvant therapy, 6 mg/kg every 3 weeks for 1 year
Pediatric dose: | Safety and efficacy not established in pediatric patients; use is not recommended
Side effects: | Common side effects include infusion-related
Drug Class
Monoclonal antibody (HER2/neu receptor antagonist)
Uses & Indications
Treatment of HER2-positive breast cancer (metastatic and adjuvant settings) and gastric cancer (HER2-positive)
Storage Requirements
Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; once reconstituted, use within 24 hours if stored at room temperature or within 48 hours if refrigerated
Manufacturer & Packaging
Manufacturer: HIKMA PHARMACEUTICALS CO.LTD, JORDAN
Package Size
50ml Vial
Price & Supplier
Price in UAE: AED 7053.00
Dosage Information
Adult Dose
8 mg/kg loading dose followed by 6 mg/kg every 3 weeks for metastatic breast cancer; for adjuvant therapy, 6 mg/kg every 3 weeks for 1 year
Pediatric Dose
Safety and efficacy not established in pediatric patients; use is not recommended
Side Effects
Common side effects include infusion-related reactions, nausea, diarrhea, fatigue, headache, and rash
Contraindications & Precautions
Hypersensitivity to trastuzumab or any component of the formulation; history of severe infusion reactions
Important Warnings
Risk of cardiotoxicity (especially in patients with pre-existing heart conditions); monitor cardiac function; potential for pulmonary toxicity; may cause fetal harm if administered during pregnancy
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.