About Trastuzumab (OGIVRI)
Class: | Monoclonal antibody (HER2/neu receptor antagonist)
Use: | Treatment of HER2-positive breast cancer (metastatic and adjuvant settings) and gastric cancer
Adult dose: | 8 mg/kg loading dose, followed by 6 mg/kg every 3 weeks or 2 mg/kg weekly, depending on the treatment regimen
Pediatric dose: | Safety and efficacy not established in pediatric patients; use is not recommended
Side effects: | Common side effects include infusion-related reactions, nausea, diarrhea, fatigue, headach
Drug Class
Monoclonal antibody (HER2/neu receptor antagonist)
Uses & Indications
Treatment of HER2-positive breast cancer (metastatic and adjuvant settings) and gastric cancer
Storage Requirements
Store refrigerated at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: MYLAN PHARMACEUTICAL PRIVATE LIMITED, India
Package Size
50ml Vial
Price & Supplier
Price in UAE: AED 5444.50
Dosage Information
Adult Dose
8 mg/kg loading dose, followed by 6 mg/kg every 3 weeks or 2 mg/kg weekly, depending on the treatment regimen
Pediatric Dose
Safety and efficacy not established in pediatric patients; use is not recommended
Side Effects
Common side effects include infusion-related reactions, nausea, diarrhea, fatigue, headache, and rash
Contraindications & Precautions
Known hypersensitivity to trastuzumab or any component of the formulation; history of severe infusion reactions
Important Warnings
Risk of cardiotoxicity, particularly in patients with pre-existing heart conditions; monitor cardiac function; potential for pulmonary toxicity; may cause fetal harm if administered during pregnancy
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.