About Trastuzumab (TRAZIMERA)
Class: | Monoclonal antibody (HER2/neu receptor antagonist)
Use: | Treatment of HER2-positive breast cancer, including metastatic breast cancer and adjuvant treatment of early-stage breast cancer
Adult dose: | 8 mg/kg loading dose, followed by 6 mg/kg every 3 weeks or 2 mg/kg weekly, depending on the treatment regimen
Pediatric dose: | Safety and efficacy not established in pediatric patients; use is not recommended
Side effects: | Common side effects include fever, chills, nausea, vomit
Drug Class
Monoclonal antibody (HER2/neu receptor antagonist)
Uses & Indications
Treatment of HER2-positive breast cancer, including metastatic breast cancer and adjuvant treatment of early-stage breast cancer
Storage Requirements
Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; once reconstituted, use within 24 hours if stored at room temperature or within 48 hours if refrigerated
Manufacturer & Packaging
Manufacturer: Pfizer Canada ULC, Canada
Package Size
1 Glass Vial (15 ml)
Price & Supplier
Price in UAE: AED 2534.50
Dosage Information
Adult Dose
8 mg/kg loading dose, followed by 6 mg/kg every 3 weeks or 2 mg/kg weekly, depending on the treatment regimen
Pediatric Dose
Safety and efficacy not established in pediatric patients; use is not recommended
Side Effects
Common side effects include fever, chills, nausea, vomiting, diarrhea, fatigue, headache, rash, and infusion-related reactions
Contraindications & Precautions
Known hypersensitivity to trastuzumab or any component of the formulation; caution in patients with a history of cardiac disease
Important Warnings
Risk of cardiotoxicity, especially in patients receiving anthracycline-containing regimens; monitor cardiac function; potential for infusion-related reactions; pregnancy category D (risk to fetus)
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.