Trastuzumab Deruxtecan (ENHERTU) – Uses, Dosage & Brands in UAE

About Trastuzumab Deruxtecan

Class: | Antineoplastic agent; HER2-directed antibody-drug conjugate Use: | Treatment of adult patients with unresectable or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens; treatment of adult patients with locally advanced or metastatic HER2-positive gastric or gastroesophageal junction adenocarcinoma who have received a prior trastuzumab-based regimen Adult dose: | Breast cancer: 5.4 mg/kg intravenously every 3 weeks (21-day cycle); Gastr

Drug Class

Antineoplastic agent; HER2-directed antibody-drug conjugate

Uses & Indications

Treatment of adult patients with unresectable or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens; treatment of adult patients with locally advanced or metastatic HER2-positive gastric or gastroesophageal junction adenocarcinoma who have received a prior trastuzumab-based regimen

Storage Requirements

Store vials in a refrigerator at 2°C to 8°C (36°F to 46°F) in the original carton to protect from light; do not freeze

Manufacturer & Packaging

Manufacturer: Daiichi Sankyo UK Ltd, United Kingdom

Package Size

Vial

Price & Supplier

Price in UAE: AED 18187.86

Dosage Information

Adult Dose

Breast cancer: 5.4 mg/kg intravenously every 3 weeks (21-day cycle); Gastric cancer: 6.4 mg/kg intravenously every 3 weeks (21-day cycle)

Pediatric Dose

Not applicable; safety and efficacy in pediatric patients have not been established

Side Effects

Nausea, fatigue, vomiting, alopecia, constipation, decreased appetite, anemia, diarrhea, neutropenia, thrombocytopenia

Important Warnings

Risk of interstitial lung disease and pneumonitis, which can be fatal; monitor for signs and symptoms of lung disease; embryo-fetal toxicity; advise females of reproductive potential to use effective contraception

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

Trastuzumab Deruxtecan – Uses, Dosage, and Brands in UAE