About Treosulfan
Class: | Alkylating agent
Use: | Treosulfan is indicated for use in conditioning regimens prior to hematopoietic stem cell transplantation in patients with hematological malignancies.
Adult dose: | The standard adult dosing for treosulfan is typically 10 g/m² administered intravenously on days -6 and -5 prior to transplantation, but dosing may vary based on specific protocols and patient conditions.
Pediatric dose: | Pediatric dosing is generally based on body surface area and should be de
Drug Class
Alkylating agent
Uses & Indications
Treosulfan is indicated for use in conditioning regimens prior to hematopoietic stem cell transplantation in patients with hematological malignancies.
Storage Requirements
Store at room temperature (15°C to 25°C) in a tightly closed container, protected from light. Reconstituted solutions should be used immediately or stored at 2°C to 8°C and used within 24 hours.
Manufacturer & Packaging
Manufacturer: Medac GmbH, GERMANY
Package Size
Vial x 5's
Price & Supplier
Price in UAE: AED 16547.29
Dosage Information
Adult Dose
The standard adult dosing for treosulfan is typically 10 g/m² administered intravenously on days -6 and -5 prior to transplantation, but dosing may vary based on specific protocols and patient conditions.
Pediatric Dose
Pediatric dosing is generally based on body surface area and should be determined by a healthcare professional; common regimens may mirror adult dosing but require careful adjustment.
Side Effects
Common side effects include nausea, vomiting, diarrhea, mucositis, myelosuppression (neutropenia, thrombocytopenia), and increased risk of infections.
Contraindications & Precautions
Treosulfan is contraindicated in patients with known hypersensitivity to treosulfan or any of its components, and in patients with severe renal impairment.
Important Warnings
Treosulfan can cause severe myelosuppression, leading to increased risk of infections and bleeding. It should be used with caution in patients with renal impairment and requires monitoring of blood counts during treatment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.