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Voretigene Neparvovec – Uses, Dosage, and Brands in UAE

Brand Name: LUXTURNA
Strength: 5 Trillion Vector genomes /ml | Form: Suspension for Intraocular Administration
Price in UAE: AED 1881560.50
Available in UAE pharmacies

About Voretigene Neparvovec

Class: | Gene therapy, Retinal gene therapy Use: | Treatment of inherited retinal disease caused by RPE65 gene mutations, leading to vision loss Adult dose: | 1.5 x 10^11 vector genomes (5 trillion vector genomes/ml) administered as a single intraocular injection per affected eye Pediatric dose: | 1.5 x 10^11 vector genomes (5 trillion vector genomes/ml) administered as a single intraocular injection per affected eye; approved for patients aged 1 year and older Side effects: | Intraocula

Drug Class

Gene therapy, Retinal gene therapy

Uses & Indications

Treatment of inherited retinal disease caused by RPE65 gene mutations, leading to vision loss

Storage Requirements

Store at -80°C (-112°F) or colder; do not store in a refrigerator or at room temperature; protect from light

Manufacturer & Packaging

Manufacturer: NOVARTIS EUROPHARM LIMITED, IRELAND

Package Size

1 vial of concentrate (2 mL cyclic olefin polymer vial) and 2 vials of solvent (2 mL cyclic olefin polymer vial)

Price & Supplier

Price in UAE: AED 1881560.50

Dosage Information

Adult Dose

1.5 x 10^11 vector genomes (5 trillion vector genomes/ml) administered as a single intraocular injection per affected eye

Pediatric Dose

1.5 x 10^11 vector genomes (5 trillion vector genomes/ml) administered as a single intraocular injection per affected eye; approved for patients aged 1 year and older

Side Effects

Intraocular inflammation, increased intraocular pressure, retinal detachment, cataract formation, visual disturbances

Contraindications & Precautions

Hypersensitivity to any component of the product; pre-existing retinal disease not caused by RPE65 mutations

Important Warnings

Risk of endophthalmitis; patients should be monitored for signs of inflammation and other ocular complications; not recommended for patients with advanced retinal degeneration or other ocular conditions that may affect treatment efficacy

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

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