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Zolbetuximab – Uses, Dosage, and Brands in UAE

Brand Name: Vyloy
Strength: 100 mg/Vial | Form: Powder for Concentrate for Solution for Infusion.
Price in UAE: AED 2749.50
Available in UAE pharmacies

About Zolbetuximab

Class: | Monoclonal antibody (anti-CLDN18.2) Use: | Treatment of adults with locally advanced or metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma expressing CLDN18.2, in combination with chemotherapy Adult dose: | 100 mg/m² administered as an intravenous infusion every 2 weeks, in combination with chemotherapy Pediatric dose: | Safety and efficacy have not been established in pediatric patients Side effects: | Nausea, vomiting, diarrhea, fatigue, infusion-related reac

Drug Class

Monoclonal antibody (anti-CLDN18.2)

Uses & Indications

Treatment of adults with locally advanced or metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma expressing CLDN18.2, in combination with chemotherapy

Storage Requirements

Store refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.

Manufacturer & Packaging

Manufacturer: Astellas Pharma Europe B.V., NETHERLANDS

Package Size

1's Glass Vial (20ml)

Price & Supplier

Price in UAE: AED 2749.50

Dosage Information

Adult Dose

100 mg/m² administered as an intravenous infusion every 2 weeks, in combination with chemotherapy

Pediatric Dose

Safety and efficacy have not been established in pediatric patients

Side Effects

Nausea, vomiting, diarrhea, fatigue, infusion-related reactions, decreased appetite, and rash

Contraindications & Precautions

Hypersensitivity to zolbetuximab or any component of the formulation; caution in patients with a history of severe infusion reactions

Important Warnings

Risk of infusion-related reactions; monitor patients during and after infusion. Potential for severe nausea and vomiting; prophylaxis with antiemetics is recommended.

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

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