About Aandexanet Alfa
Class: | Antidote, Factor Xa Inhibitor Reversal Agent
Use: | Reversal of anticoagulation effects of factor Xa inhibitors (e.g., apixaban, rivaroxaban) in patients with life-threatening or uncontrolled bleeding
Adult dose: | 200 mg administered as a slow intravenous injection; may repeat with an additional 200 mg dose if needed, based on clinical response
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended for use in this population
Side effects: |
Drug Class
Antidote, Factor Xa Inhibitor Reversal Agent
Uses & Indications
Reversal of anticoagulation effects of factor Xa inhibitors (e.g., apixaban, rivaroxaban) in patients with life-threatening or uncontrolled bleeding
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; may be stored at room temperature (up to 25°C or 77°F) for up to 8 hours after removal from refrigeration
Manufacturer & Packaging
Manufacturer: PORTOLA, Germany
Package Size
4's
Price & Supplier
Price in UAE: AED 74740.00
Dosage Information
Adult Dose
200 mg administered as a slow intravenous injection; may repeat with an additional 200 mg dose if needed, based on clinical response
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in this population
Side Effects
Thromboembolic events, infusion site reactions, headache, nausea, fatigue, and hypersensitivity reactions
Contraindications & Precautions
Known hypersensitivity to andexanet alfa or any component of the formulation; not recommended in patients with active bleeding due to a coagulopathy
Important Warnings
Risk of thromboembolic events; monitor for signs of thrombosis; use caution in patients with a history of cardiovascular disease; not intended for use in patients with life-threatening bleeding due to other causes or in patients receiving anticoagulants other than factor Xa inhibitors
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.