About Riociguat (micronized)
            
            Class: | Guanylate cyclase stimulator  
Use: | Treatment of pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH)  
Adult dose: | Initial dose of 1 mg three times daily, may be increased to a maximum of 2.5 mg three times daily based on tolerance and efficacy  
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended for use in children  
Side effects: | Headache, dizziness, nausea, diarrhea, hypotension, and dyspepsia
         
        
            
                
                
                    
                        Drug Class
                    
                    Guanylate cyclase stimulator
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH)
                 
                
                
                    
                        Storage Requirements
                    
                    Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Bayer Pharma AG, GERMANY
                    
                    
                    Package Size
                    42's (14's Blister x 3)
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 8318.50
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        Initial dose of 1 mg three times daily, may be increased to a maximum of 2.5 mg three times daily based on tolerance and efficacy
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy not established in pediatric patients; not recommended for use in children
                    
                 
                
                
                    
                        Side Effects
                    
                    Headache, dizziness, nausea, diarrhea, hypotension, and dyspepsia
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Pregnancy, concomitant use with nitrates or nitric oxide donors, severe hepatic impairment
         
        
        
            
                Important Warnings
            
            Risk of hypotension, must monitor blood pressure regularly; not to be used in patients with pulmonary hypertension due to left heart disease
         
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.