About Doxorubicin Hydrochloride
Class: | Anthracycline antibiotic, Antineoplastic agent
Use: | Doxorubicin Hydrochloride is used for the treatment of various cancers, including breast cancer, ovarian cancer, bladder cancer, lung cancer, and certain types of leukemia and lymphoma.
Adult dose: | The standard adult dose varies depending on the specific cancer being treated, the regimen used, and patient factors. Typically, it is administered intravenously at a dose of 60-75 mg/m² every 21 days when used as a single agent. In co
Drug Class
Anthracycline antibiotic, Antineoplastic agent
Uses & Indications
Doxorubicin Hydrochloride is used for the treatment of various cancers, including breast cancer, ovarian cancer, bladder cancer, lung cancer, and certain types of leukemia and lymphoma.
Storage Requirements
Store at 2°C to 8°C (36°F to 46°F). Protect from light. Do not freeze. Once reconstituted, the solution should be used immediately or stored under refrigeration and used within 24 hours.
Manufacturer & Packaging
Manufacturer: Pfizer Italia S.r.l., ITALY
Package Size
1 Vial
Price & Supplier
Price in UAE: AED 105.28
Dosage Information
Adult Dose
The standard adult dose varies depending on the specific cancer being treated, the regimen used, and patient factors. Typically, it is administered intravenously at a dose of 60-75 mg/m² every 21 days when used as a single agent. In combination therapy, the dose may be adjusted to 40-60 mg/m² every 21-28 days.
Pediatric Dose
Pediatric dosing is highly individualized based on the type of cancer, protocol, and patient-specific factors. Doses typically range from 30-75 mg/m² per cycle, administered intravenously.
Side Effects
Common side effects include nausea, vomiting, hair loss, mouth sores, fatigue, and myelosuppression (decreased blood cell counts). Cardiotoxicity is a significant risk, especially with cumulative doses.
Contraindications & Precautions
Contraindicated in patients with severe myocardial insufficiency, recent myocardial infarction, severe arrhythmias, and hypersensitivity to doxorubicin or any component of the formulation. It should not be used in patients with severe hepatic impairment.
Important Warnings
Doxorubicin can cause severe local tissue necrosis if extravasation occurs. It has a dose-dependent risk of cardiotoxicity, which can lead to congestive heart failure. Monitor cardiac function before and during treatment. It may cause secondary malignancies such as leukemia. Use with caution in patients with hepatic impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.