About Afatinib Dimaleate
Class: | Tyrosine kinase inhibitor
Use: | Treatment of patients with non-small cell lung cancer (NSCLC) with specific epidermal growth factor receptor (EGFR) mutations
Adult dose: | 40 mg orally once daily; may be reduced to 30 mg or 20 mg based on tolerability
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Diarrhea, rash, stomatitis, decreased appetite, nausea, fatigue
Contraindications: | Hypersensitivity to afatinib or any component of th
Drug Class
Tyrosine kinase inhibitor
Uses & Indications
Treatment of patients with non-small cell lung cancer (NSCLC) with specific epidermal growth factor receptor (EGFR) mutations
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Boehringer Ingelheim International GmbH, GERMANY
Package Size
28's (7's Blister x 4)
Price & Supplier
Price in UAE: AED 12023.00
Dosage Information
Adult Dose
40 mg orally once daily; may be reduced to 30 mg or 20 mg based on tolerability
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Diarrhea, rash, stomatitis, decreased appetite, nausea, fatigue
Contraindications & Precautions
Hypersensitivity to afatinib or any component of the formulation; pregnancy and breastfeeding
Important Warnings
Risk of interstitial lung disease (ILD), liver toxicity, and severe skin reactions; monitor for signs of ILD and liver function; use caution in patients with pre-existing lung disease or liver impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.