Agalsidase alfa (REPLAGAL) – Uses, Dosage & Brands in UAE

About Agalsidase alfa

Class: | Enzyme replacement therapy (ERT) Use: | Treatment of Fabry disease (alpha-galactosidase A deficiency) to reduce the accumulation of globotriaosylceramide (Gb3) in various tissues Adult dose: | 0.2 mg/kg body weight administered every two weeks as an intravenous infusion Pediatric dose: | 0.2 mg/kg body weight administered every two weeks as an intravenous infusion for patients aged 8 years and older; safety and efficacy in younger children have not been established Side effects:

Drug Class

Enzyme replacement therapy (ERT)

Uses & Indications

Treatment of Fabry disease (alpha-galactosidase A deficiency) to reduce the accumulation of globotriaosylceramide (Gb3) in various tissues

Storage Requirements

Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; once diluted, the solution should be used immediately or stored at 2°C to 8°C for up to 24 hours

Manufacturer & Packaging

Manufacturer: Shire Human Genetic Therapies AB, SWEDEN

Package Size

GLASS VIAL

Price & Supplier

Price in UAE: AED 8055.50

Dosage Information

Adult Dose

0.2 mg/kg body weight administered every two weeks as an intravenous infusion

Pediatric Dose

0.2 mg/kg body weight administered every two weeks as an intravenous infusion for patients aged 8 years and older; safety and efficacy in younger children have not been established

Side Effects

Headache, infusion-related reactions (such as chills, fever, and rash), abdominal pain, nausea, diarrhea, fatigue, and joint pain

Important Warnings

Risk of hypersensitivity reactions; monitor patients during and after infusion; consider premedication with antihistamines or corticosteroids in patients with a history of allergic reactions; patients should be informed about the potential for infusion-related reactions

Other Brands & Strengths Available in UAE

Different brands and strengths of Agalsidase alfa available in UAE pharmacies:

REPLAGAL 1 mg/ml Concentrate For Dilution For Infusion REPLAGAL 1 mg/ml Concentrate For Dilution For Infusion

Related Medicines in Same Category

See also: Other Enzyme replacement therapy (ERT) medicines available in UAE pharmacies

Agalsidase beta Agalsidase beta Alfa Glucosidaze-Myozyme Alfa Glucosidaze-Myozyme Galsulfase Galsulfase Idursulfase Imiglucerase

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

Agalsidase alfa – Uses, Dosage, and Brands in UAE