About NIRAPARIB,Abiraterone Acetate
**NIRAPARIB**
Class: | PARP inhibitor
Use: | Treatment of patients with recurrent ovarian cancer who have responded to platinum-based chemotherapy; also used in certain breast cancers with BRCA mutations.
Adult dose: | Initial dose of 300 mg orally once daily.
Pediatric dose: | Safety and efficacy not established in pediatric patients.
Side effects: | Fatigue, nausea, vomiting, anemia, thrombocytopenia, elevated liver enzymes.
Contraindications: | Hypersensitivity to niraparib or any
Drug Class
Androgen biosynthesis inhibitor
Uses & Indications
Treatment of metastatic castration-resistant prostate cancer (mCRPC) in combination with prednisone.
Storage Requirements
Store at room temperature, 20°C to 25°C (68°F to 77°F); protect from moisture and light.
Manufacturer & Packaging
Manufacturer: Janseen Cilag International, Belgium
Package Size
56's (28's Wallet X 2 (14's Blister X 2 )
Price & Supplier
Price in UAE: AED 27810.00
Dosage Information
Adult Dose
1000 mg (two 500 mg tablets) orally once daily, taken on an empty stomach.
Pediatric Dose
Safety and efficacy not established in pediatric patients.
Side Effects
Fatigue, hypertension, hypokalemia, joint pain, liver function abnormalities.
Contraindications & Precautions
Hypersensitivity to abiraterone or any component; pregnancy; concurrent use of strong CYP2D6 inhibitors.
Important Warnings
Risk of hepatotoxicity; monitor liver function; may cause adrenal insufficiency; contraindicated in pregnancy.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.