About Amrinone
Class: | Phosphodiesterase inhibitor
Use: | Treatment of acute heart failure and severe congestive heart failure; used to improve cardiac output and reduce systemic vascular resistance
Adult dose: | Initial dose: 0.5 to 1 mg/kg IV bolus; Maintenance: 2.5 to 10 mcg/kg/min IV infusion, adjusted based on clinical response
Pediatric dose: | Not established; use in pediatric patients is not well studied and should be approached with caution
Side effects: | Common side effects include hypotens
Drug Class
Phosphodiesterase inhibitor
Uses & Indications
Treatment of acute heart failure and severe congestive heart failure; used to improve cardiac output and reduce systemic vascular resistance
Storage Requirements
Store at room temperature (20-25°C or 68-77°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: Sterling Winthrop, U.S.A
Package Size
20ml Ampoule
Price & Supplier
Price in UAE: AED 69.50
Dosage Information
Adult Dose
Initial dose: 0.5 to 1 mg/kg IV bolus; Maintenance: 2.5 to 10 mcg/kg/min IV infusion, adjusted based on clinical response
Pediatric Dose
Not established; use in pediatric patients is not well studied and should be approached with caution
Side Effects
Common side effects include hypotension, arrhythmias, headache, nausea, vomiting, and thrombocytopenia
Contraindications & Precautions
Hypersensitivity to amrinone or any component of the formulation; severe aortic or pulmonary valvular disease; obstructive hypertrophic cardiomyopathy; significant hypotension
Important Warnings
Monitor for hypotension and arrhythmias; use with caution in patients with renal impairment; may cause thrombocytopenia; not recommended for long-term use due to potential for increased mortality in chronic heart failure patients
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.