About Milrinone
Class: | Phosphodiesterase inhibitor
Use: | Treatment of acute heart failure and severe chronic heart failure; used to improve cardiac output and reduce pulmonary vascular resistance
Adult dose: | Initial bolus of 50 mcg/kg IV over 10 minutes, followed by a continuous infusion of 0.375 to 0.75 mcg/kg/min; titrate based on clinical response
Pediatric dose: | Not established; use in pediatric patients should be based on clinical judgment and specific patient circumstances
Side effects: | H
Drug Class
Phosphodiesterase inhibitor
Uses & Indications
Treatment of acute heart failure and severe chronic heart failure; used to improve cardiac output and reduce pulmonary vascular resistance
Storage Requirements
Store at 20-25°C (68-77°F); protect from light; do not freeze; discard unused portion after 24 hours if not refrigerated
Manufacturer & Packaging
Manufacturer: Baxter Healthcare Corporation (Deerfield), U.S.A
Package Size
1 Injection x 10ml
Price & Supplier
Price in UAE: AED 48.60
Dosage Information
Adult Dose
Initial bolus of 50 mcg/kg IV over 10 minutes, followed by a continuous infusion of 0.375 to 0.75 mcg/kg/min; titrate based on clinical response
Pediatric Dose
Not established; use in pediatric patients should be based on clinical judgment and specific patient circumstances
Side Effects
Hypotension, arrhythmias, headache, nausea, vomiting, thrombocytopenia, and increased heart rate
Contraindications & Precautions
Hypersensitivity to milrinone or any component of the formulation; severe aortic or pulmonary valve disease; obstructive hypertrophic cardiomyopathy
Important Warnings
Monitor for hypotension and arrhythmias; use with caution in patients with renal impairment; may cause increased mortality in patients with chronic heart failure when used long-term; not recommended for use in patients with severe hypotension or hypovolemia without appropriate volume resuscitation
Related Medicines in Same Category
See also: Other Phosphodiesterase inhibitor medicines available in UAE pharmacies
Amrinone
Enoximone
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.