About APREPITANT
Class: | Antiemetic, Neurokinin-1 (NK1) receptor antagonist
Use: | Prevention of nausea and vomiting associated with chemotherapy, particularly highly emetogenic chemotherapy; prevention of postoperative nausea and vomiting
Adult dose: | 40 mg orally, administered 1 hour prior to chemotherapy on Day 1; may be used in combination with other antiemetics
Pediatric dose: | Not established for children under 12 years; for children 12 years and older, the recommended dose is 125 mg orally on Day
Drug Class
Antiemetic, Neurokinin-1 (NK1) receptor antagonist
Uses & Indications
Prevention of nausea and vomiting associated with chemotherapy, particularly highly emetogenic chemotherapy; prevention of postoperative nausea and vomiting
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture
Manufacturer & Packaging
Manufacturer: Glenmark Pharmaceutical Inc., U.S.A
Package Size
1's
Price & Supplier
Price in UAE: AED 276.58
Dosage Information
Adult Dose
40 mg orally, administered 1 hour prior to chemotherapy on Day 1; may be used in combination with other antiemetics
Pediatric Dose
Not established for children under 12 years; for children 12 years and older, the recommended dose is 125 mg orally on Day 1, followed by 80 mg once daily on Days 2 and 3
Side Effects
Fatigue, dizziness, diarrhea, constipation, loss of appetite, headache, and hiccups
Contraindications & Precautions
Hypersensitivity to aprepitant or any component of the formulation; use with caution in patients with hepatic impairment
Important Warnings
May cause increased risk of bleeding when used with anticoagulants; potential for drug interactions due to CYP3A4 metabolism; not recommended for use in pregnancy unless clearly needed; monitor for signs of allergic reactions
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.