About AVALGLUCOSIDASE ALFA
Class: | Enzyme replacement therapy
Use: | Treatment of Pompe disease (glycogen storage disease type II) in patients of all ages
Adult dose: | 20 mg/kg body weight administered every two weeks via intravenous infusion
Pediatric dose: | 20 mg/kg body weight administered every two weeks via intravenous infusion
Side effects: | Infusion-related reactions (fever, chills, rash), headache, nausea, vomiting, diarrhea, abdominal pain, fatigue
Contraindications: | Hypersensitivity to avalglucos
Drug Class
Enzyme replacement therapy
Uses & Indications
Treatment of Pompe disease (glycogen storage disease type II) in patients of all ages
Storage Requirements
Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; once reconstituted, use immediately or store at 2°C to 8°C for up to 24 hours
Manufacturer & Packaging
Manufacturer: Genzyme Europe B.V., NETHERLANDS
Package Size
1 Glass Vial
Price & Supplier
Price in UAE: AED 7965.50
Dosage Information
Adult Dose
20 mg/kg body weight administered every two weeks via intravenous infusion
Pediatric Dose
20 mg/kg body weight administered every two weeks via intravenous infusion
Side Effects
Infusion-related reactions (fever, chills, rash), headache, nausea, vomiting, diarrhea, abdominal pain, fatigue
Contraindications & Precautions
Hypersensitivity to avalglucosidase alfa or any component of the formulation; caution in patients with a history of severe allergic reactions
Important Warnings
Risk of serious allergic reactions; monitor patients for signs of hypersensitivity during and after infusion; consider premedication with antihistamines or corticosteroids for patients with a history of allergic reactions
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.