About Blinatumomab
Class: | Monoclonal antibody (bispecific T-cell engager)
Use: | Treatment of adult and pediatric patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL)
Adult dose: | Initial dose of 9 mcg/day for the first 7 days, followed by 28 mcg/day for subsequent cycles, administered as a continuous intravenous infusion
Pediatric dose: | Initial dose of 5 mcg/m²/day for the first 7 days, followed by 15 mcg/m²/day for subsequent cycles, administered as a continuous int
Drug Class
Monoclonal antibody (bispecific T-cell engager)
Uses & Indications
Treatment of adult and pediatric patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL)
Storage Requirements
Store lyophilized powder at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; reconstituted solution should be used immediately or stored at 2°C to 8°C for up to 24 hours
Manufacturer & Packaging
Manufacturer: Amgen Inc., U.S.A
Package Size
1 Glass Vial + 1 Glass Vial of Solution Stabilizer
Price & Supplier
Price in UAE: AED 15748.00
Dosage Information
Adult Dose
Initial dose of 9 mcg/day for the first 7 days, followed by 28 mcg/day for subsequent cycles, administered as a continuous intravenous infusion
Pediatric Dose
Initial dose of 5 mcg/m²/day for the first 7 days, followed by 15 mcg/m²/day for subsequent cycles, administered as a continuous intravenous infusion
Side Effects
Cytokine release syndrome, neurological events (including seizures), fever, headache, nausea, fatigue, and infections
Contraindications & Precautions
Hypersensitivity to blinatumomab or any component of the formulation; caution in patients with a history of severe neurological disorders
Important Warnings
Monitor for cytokine release syndrome and neurological toxicities; ensure availability of supportive care; patients should be monitored closely during the first week of treatment and after dose adjustments
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.