About Teclistamab
Class: | Monoclonal antibody (bispecific T-cell engager)
Use: | Treatment of adult patients with relapsed or refractory multiple myeloma who have received at least three prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.
Adult dose: | Initial dose of 1.5 mg/kg administered subcutaneously on Day 1, followed by 3 mg/kg on Day 8, and then 6 mg/kg on Day 15 and every subsequent week thereafter.
Pediatric dose: | Safety and
Drug Class
Monoclonal antibody (bispecific T-cell engager)
Uses & Indications
Treatment of adult patients with relapsed or refractory multiple myeloma who have received at least three prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Manufacturer & Packaging
Manufacturer: Janseen Cilag International, Belgium
Package Size
3mL Glass Vial
Price & Supplier
Price in UAE: AED 4744.50
Dosage Information
Adult Dose
Initial dose of 1.5 mg/kg administered subcutaneously on Day 1, followed by 3 mg/kg on Day 8, and then 6 mg/kg on Day 15 and every subsequent week thereafter.
Pediatric Dose
Safety and efficacy have not been established in pediatric patients; not recommended for use in this population.
Side Effects
Common side effects include cytokine release syndrome (CRS), fatigue, nausea, diarrhea, anemia, thrombocytopenia, and neutropenia.
Contraindications & Precautions
Hypersensitivity to teclistamab or any component of the formulation; caution in patients with a history of severe CRS or neurological toxicities.
Important Warnings
Risk of severe or life-threatening CRS; monitor patients closely for signs and symptoms. Risk of neurological toxicities, including encephalopathy; consider discontinuation if severe symptoms occur.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.