About delandistrogene moxeparvovec 1.33 x 10¹⁴ vector genomes
Class: | Gene therapy product
Use: | Treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation in the dystrophin gene
Adult dose: | Not applicable; primarily indicated for pediatric patients
Pediatric dose: | 1.33 x 10¹⁴ vector genomes per kg body weight, administered as a single intravenous infusion
Side effects: | Common side effects include fever, headache, fatigue, nausea, vomiting, and infusion-related reactions
Contraindications: | Hypersensitivity to a
Drug Class
Gene therapy product
Uses & Indications
Treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation in the dystrophin gene
Storage Requirements
Store in a refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: F. Hoffmann-La Roche Ltd [Basel; Switzerland], Switzerland
Package Size
1 treatment pack (10-35 or 36-70 vials/ Kit)
Price & Supplier
Price in UAE: AED 10276000.00
Dosage Information
Adult Dose
Not applicable; primarily indicated for pediatric patients
Pediatric Dose
1.33 x 10¹⁴ vector genomes per kg body weight, administered as a single intravenous infusion
Side Effects
Common side effects include fever, headache, fatigue, nausea, vomiting, and infusion-related reactions
Contraindications & Precautions
Hypersensitivity to any component of the product; caution in patients with pre-existing liver disease or elevated liver enzymes
Important Warnings
Risk of serious liver enzyme elevation; monitor liver function tests; potential for immune response to the vector; not recommended for patients with significant cardiac or respiratory conditions
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.