About Exagamglogene autotemcel
Class: | Gene therapy product
Use: | Treatment of beta-thalassemia in patients who require regular red blood cell transfusions and have a specific genetic mutation
Adult dose: | Not applicable; primarily used in pediatric patients
Pediatric dose: | Administered as a single dose of 4 M-13M CD34 cells/mL, specific dosing based on patient weight and clinical guidelines
Side effects: | Common side effects include fever, headache, fatigue, nausea, and infusion-related reactions
Contraindica
Drug Class
Gene therapy product
Uses & Indications
Treatment of beta-thalassemia in patients who require regular red blood cell transfusions and have a specific genetic mutation
Storage Requirements
Store at -196°C in liquid nitrogen; do not store at temperatures above -150°C
Manufacturer & Packaging
Manufacturer: Vertex Pharmaceuticals Limited, UNITED KINGDOM
Package Size
One Carton contains multiple vials (Each vial contains 1.5ML to 20ML)
Price & Supplier
Price in UAE: AED 10804525.50
Dosage Information
Adult Dose
Not applicable; primarily used in pediatric patients
Pediatric Dose
Administered as a single dose of 4 M-13M CD34 cells/mL, specific dosing based on patient weight and clinical guidelines
Side Effects
Common side effects include fever, headache, fatigue, nausea, and infusion-related reactions
Contraindications & Precautions
Hypersensitivity to any component of the product; active infections; certain hematologic malignancies
Important Warnings
Risk of serious adverse reactions including infusion-related reactions; potential for long-term effects not yet fully understood; monitor for signs of infection and malignancy post-treatment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.