About Difelikefalin
Class: | Opioid receptor agonist
Use: | Treatment of pruritus associated with chronic kidney disease in adults on dialysis
Adult dose: | 0.5 mcg/kg IV bolus, administered over 30 seconds, up to 3 times per week
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Nausea, vomiting, dizziness, headache, sedation, diarrhea
Contraindications: | Hypersensitivity to difelikefalin or any component of the formulation; opioid use in patients with a history
Drug Class
Opioid receptor agonist
Uses & Indications
Treatment of pruritus associated with chronic kidney disease in adults on dialysis
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: Vifor Fresenius Medical Care Renal Pharma France, France
Package Size
1ml Vial x 12's
Price & Supplier
Price in UAE: AED 2619.18
Dosage Information
Adult Dose
0.5 mcg/kg IV bolus, administered over 30 seconds, up to 3 times per week
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Nausea, vomiting, dizziness, headache, sedation, diarrhea
Contraindications & Precautions
Hypersensitivity to difelikefalin or any component of the formulation; opioid use in patients with a history of substance use disorder
Important Warnings
Risk of opioid-related adverse reactions; monitor for respiratory depression; potential for abuse and dependence; use with caution in patients with a history of substance use disorder or respiratory conditions
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.