About Durvalumab
Class: | Monoclonal antibody (PD-L1 inhibitor)
Use: | Treatment of unresectable stage III non-small cell lung cancer (NSCLC) in patients whose disease has not progressed following platinum-based chemotherapy and radiation therapy; also indicated for the treatment of locally advanced or metastatic urothelial carcinoma.
Adult dose: | 10 mg/kg administered intravenously every 2 weeks.
Pediatric dose: | Safety and efficacy have not been established in pediatric patients; not recommended for us
Drug Class
Monoclonal antibody (PD-L1 inhibitor)
Uses & Indications
Treatment of unresectable stage III non-small cell lung cancer (NSCLC) in patients whose disease has not progressed following platinum-based chemotherapy and radiation therapy; also indicated for the treatment of locally advanced or metastatic urothelial carcinoma.
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Manufacturer & Packaging
Manufacturer: AstraZeneca UK Limited, UNITED KINGDOM
Package Size
2.4ml Vial
Price & Supplier
Price in UAE: AED 4292.50
Dosage Information
Adult Dose
10 mg/kg administered intravenously every 2 weeks.
Pediatric Dose
Safety and efficacy have not been established in pediatric patients; not recommended for use in this population.
Side Effects
Fatigue, nausea, decreased appetite, cough, dyspnea, rash, diarrhea, and infusion-related reactions.
Contraindications & Precautions
History of severe hypersensitivity reactions to durvalumab or any component of the formulation; caution in patients with autoimmune diseases or those receiving immunosuppressive therapy.
Important Warnings
Immune-mediated adverse reactions may occur, including pneumonitis, colitis, hepatitis, endocrinopathies, and nephritis. Monitor for signs and symptoms and manage accordingly. Discontinue therapy for severe reactions.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.