About Pegcetacoplan
Class: | Complement inhibitor
Use: | Treatment of adult patients with paroxysmal nocturnal hemoglobinuria (PNH)
Adult dose: | 1 mg/kg administered as a subcutaneous injection once weekly, with an initial loading dose of 1 mg/kg on day 1, followed by 1 mg/kg on days 8 and 15
Pediatric dose: | Safety and efficacy have not been established in pediatric patients
Side effects: | Injection site reactions, headache, diarrhea, nausea, fatigue, and abdominal pain
Contraindications: | Hypersensi
Drug Class
Complement inhibitor
Uses & Indications
Treatment of adult patients with paroxysmal nocturnal hemoglobinuria (PNH)
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; may be stored at room temperature (up to 25°C or 77°F) for up to 30 days
Manufacturer & Packaging
Manufacturer: Swedish Orphan Biovitrum AB, SWEDEN
Package Size
1 Glass vial
Price & Supplier
Price in UAE: AED 15612.50
Dosage Information
Adult Dose
1 mg/kg administered as a subcutaneous injection once weekly, with an initial loading dose of 1 mg/kg on day 1, followed by 1 mg/kg on days 8 and 15
Pediatric Dose
Safety and efficacy have not been established in pediatric patients
Side Effects
Injection site reactions, headache, diarrhea, nausea, fatigue, and abdominal pain
Contraindications & Precautions
Hypersensitivity to pegcetacoplan or any component of the formulation; active serious infections
Important Warnings
Risk of serious infections, including meningococcal infections; patients should be vaccinated against meningococcal disease prior to starting treatment; monitor for signs of infection during therapy
Related Medicines in Same Category
See also: Other Complement inhibitor medicines available in UAE pharmacies
Avacopan
Danicopan,Danicopan
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.