About Estradiol,Norethisterone Acetate
            
            Class: | Hormone Replacement Therapy (HRT) - Combination of Estrogen and Progestin
Use: | Used for the treatment of menopausal symptoms such as hot flashes, prevention of osteoporosis in postmenopausal women, and to address estrogen deficiency symptoms.
Adult dose: | Apply one transdermal patch (Estradiol 4 mg/Norethisterone Acetate 10 mg) to the skin twice weekly. The patch should be replaced every 3 to 4 days.
Pediatric dose: | Not applicable; not indicated for use in pediatric patients.
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                        Drug Class
                    
                    Hormone Replacement Therapy (HRT) - Combination of Estrogen and Progestin
                 
                
                
                    
                        Uses & Indications
                    
                    Used for the treatment of menopausal symptoms such as hot flashes, prevention of osteoporosis in postmenopausal women, and to address estrogen deficiency symptoms.
                 
                
                
                    
                        Storage Requirements
                    
                    Store at room temperature, away from direct sunlight and moisture. Keep in the original packaging until ready to use.
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Ciba Geigy, SWITZERLAND
                    
                    
                    Package Size
                    4 Sachets (Estraderm) + 4 Sachets (Estragest)
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 89.50
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        Apply one transdermal patch (Estradiol 4 mg/Norethisterone Acetate 10 mg) to the skin twice weekly. The patch should be replaced every 3 to 4 days.
                    
                    
                        Pediatric Dose
                    
                    
                        Not applicable; not indicated for use in pediatric patients.
                    
                 
                
                
                    
                        Side Effects
                    
                    Common side effects include skin irritation at the application site, headache, breast tenderness, nausea, and mood changes.
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Contraindicated in patients with known or suspected breast cancer, estrogen-dependent neoplasia, active or history of venous thromboembolism, liver dysfunction or disease, and known hypersensitivity to any component of the patch.
         
        
        
            
                Important Warnings
            
            Increased risk of cardiovascular events, breast cancer, and venous thromboembolism. Use the lowest effective dose for the shortest duration consistent with treatment goals. Regularly monitor blood pressure and perform routine breast exams and mammograms.
         
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.