About Fluorouracil
Class: | Antimetabolite, Antineoplastic
Use: | Treatment of various cancers, including colorectal cancer, breast cancer, and other solid tumors; also used for the treatment of actinic keratosis and superficial basal cell carcinoma.
Adult dose: | Typically, 12 mg/m² to 15 mg/m² IV bolus once daily for 5 days, repeated every 4 weeks; dosing may vary based on specific cancer type and treatment protocol.
Pediatric dose: | Safety and efficacy not established; use in pediatric patients should be
Drug Class
Antimetabolite, Antineoplastic
Uses & Indications
Treatment of various cancers, including colorectal cancer, breast cancer, and other solid tumors; also used for the treatment of actinic keratosis and superficial basal cell carcinoma.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F); protect from light; do not freeze.
Manufacturer & Packaging
Manufacturer: David Bull Laboratories, AUSTRALIA
Package Size
10ml Vial x 5
Price & Supplier
Price in UAE: AED 55.00
Dosage Information
Adult Dose
Typically, 12 mg/m² to 15 mg/m² IV bolus once daily for 5 days, repeated every 4 weeks; dosing may vary based on specific cancer type and treatment protocol.
Pediatric Dose
Safety and efficacy not established; use in pediatric patients should be determined by a specialist.
Side Effects
Common side effects include nausea, vomiting, diarrhea, mucositis, myelosuppression (neutropenia, thrombocytopenia), hand-foot syndrome, and skin reactions.
Contraindications & Precautions
Known hypersensitivity to fluorouracil or any component of the formulation; patients with significant bone marrow suppression or those who are pregnant or breastfeeding.
Important Warnings
Risk of severe toxicity, including myelosuppression and gastrointestinal toxicity; monitor blood counts regularly; caution in patients with hepatic impairment; avoid use in patients with dihydropyrimidine dehydrogenase deficiency.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.