About Cytarabine
Class: | Antimetabolite, Antineoplastic agent
Use: | Cytarabine is primarily used for the treatment of acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), and chronic myelogenous leukemia (CML) in blast crisis.
Adult dose: | The dosing of Cytarabine can vary significantly based on the treatment regimen and condition being treated. For induction therapy in AML, a common regimen is 100-200 mg/m²/day by continuous IV infusion for 7 days.
Pediatric dose: | Pediatric dosing is highl
Drug Class
Antimetabolite, Antineoplastic agent
Uses & Indications
Cytarabine is primarily used for the treatment of acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), and chronic myelogenous leukemia (CML) in blast crisis.
Storage Requirements
Store at controlled room temperature, 20°C to 25°C (68°F to 77°F). Protect from light and freezing.
Manufacturer & Packaging
Manufacturer: Mayne Pharma Pty. Ltd., AUSTRALIA
Package Size
10ml Vial
Price & Supplier
Price in UAE: AED 141.50
Dosage Information
Adult Dose
The dosing of Cytarabine can vary significantly based on the treatment regimen and condition being treated. For induction therapy in AML, a common regimen is 100-200 mg/m²/day by continuous IV infusion for 7 days.
Pediatric Dose
Pediatric dosing is highly variable and should be determined by a specialist. For AML, a typical dose might be 100 mg/m²/day by continuous IV infusion for 7 days, similar to adult dosing, but adjusted for body surface area and clinical condition.
Side Effects
Common side effects include nausea, vomiting, diarrhea, mouth sores, rash, fever, and myelosuppression (leading to anemia, leukopenia, and thrombocytopenia).
Contraindications & Precautions
Contraindicated in patients with hypersensitivity to Cytarabine. Caution is advised in patients with bone marrow suppression, hepatic impairment, or active infections.
Important Warnings
Cytarabine can cause severe myelosuppression, leading to infection or bleeding. It may also cause gastrointestinal toxicity, hepatotoxicity, and neurotoxicity. Regular monitoring of blood counts and liver function tests is essential. Use with caution in patients with renal or hepatic impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.