About Amphotericin B
Class: | Antifungal agent, Polyene macrolide
Use: | Treatment of serious fungal infections, including cryptococcal meningitis in immunocompromised patients, systemic candidiasis, and fungal infections caused by Aspergillus species.
Adult dose: | Initial dose: 0.5 to 1 mg/kg/day IV; may increase to 1 to 1.5 mg/kg/day based on clinical response and tolerance.
Pediatric dose: | Initial dose: 0.5 to 1 mg/kg/day IV; may be adjusted based on clinical response and tolerance.
Side effects: | Com
Drug Class
Antifungal agent, Polyene macrolide
Uses & Indications
Treatment of serious fungal infections, including cryptococcal meningitis in immunocompromised patients, systemic candidiasis, and fungal infections caused by Aspergillus species.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F); protect from light; reconstituted solutions should be used immediately or stored at 2-8°C (36-46°F) for up to 24 hours.
Manufacturer & Packaging
Manufacturer: Bristol-Myers Squibb Pharmaceuticals Limited, UNITED KINGDOM
Package Size
Vial
Price & Supplier
Price in UAE: AED 151.00
Dosage Information
Adult Dose
Initial dose: 0.5 to 1 mg/kg/day IV; may increase to 1 to 1.5 mg/kg/day based on clinical response and tolerance.
Pediatric Dose
Initial dose: 0.5 to 1 mg/kg/day IV; may be adjusted based on clinical response and tolerance.
Side Effects
Common side effects include fever, chills, nausea, vomiting, headache, nephrotoxicity, and electrolyte imbalances (hypokalemia, hypomagnesemia).
Contraindications & Precautions
Known hypersensitivity to amphotericin B or any component of the formulation; caution in patients with renal impairment or electrolyte imbalances.
Important Warnings
Risk of serious adverse reactions including renal toxicity, infusion-related reactions, and hypokalemia; monitor renal function and electrolytes regularly during treatment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.