About Golimumab
Class: | Tumor Necrosis Factor (TNF) inhibitor
Use: | Golimumab (SIMPONI) is used for the treatment of moderate to severe rheumatoid arthritis, active psoriatic arthritis, active ankylosing spondylitis, and moderate to severe ulcerative colitis.
Adult dose: | For rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: 50 mg administered once a month as a subcutaneous injection. For ulcerative colitis: 200 mg initially, followed by 100 mg at week 2, then 100 mg every 4 weeks.
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Drug Class
Tumor Necrosis Factor (TNF) inhibitor
Uses & Indications
Golimumab (SIMPONI) is used for the treatment of moderate to severe rheumatoid arthritis, active psoriatic arthritis, active ankylosing spondylitis, and moderate to severe ulcerative colitis.
Storage Requirements
Store in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light and store in the original carton until use.
Manufacturer & Packaging
Manufacturer: Cilag AG, SWITZERLAND
Package Size
0.5ml Pre-filled Syringe
Price & Supplier
Price in UAE: AED 5561.00
Dosage Information
Adult Dose
For rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: 50 mg administered once a month as a subcutaneous injection. For ulcerative colitis: 200 mg initially, followed by 100 mg at week 2, then 100 mg every 4 weeks.
Pediatric Dose
The safety and efficacy of Golimumab in pediatric patients have not been established for all indications. Consult specific guidelines for any approved pediatric use.
Side Effects
Common side effects include upper respiratory tract infections, injection site reactions, viral infections, and nausea.
Contraindications & Precautions
Contraindicated in patients with severe infections such as sepsis, and those with known hypersensitivity to Golimumab or any of its components.
Important Warnings
Serious infections, including tuberculosis and invasive fungal infections, have been reported. Monitor for signs of infection during and after treatment. There is an increased risk of malignancies, including lymphoma. Use with caution in patients with heart failure.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.