About Guselkumab (TREMFYA)
Class: | Monoclonal antibody (IL-23 inhibitor)
Use: | Treatment of moderate to severe plaque psoriasis in adults, active psoriatic arthritis in adults, and active ankylosing spondylitis in adults.
Adult dose: | Initial dose: 100 mg subcutaneously at week 0 and week 4; Maintenance dose: 100 mg subcutaneously every 8 weeks thereafter.
Pediatric dose: | Safety and efficacy not established in pediatric patients under 18 years of age.
Side effects: | Injection site reactions, upper respirator
Drug Class
Monoclonal antibody (IL-23 inhibitor)
Uses & Indications
Treatment of moderate to severe plaque psoriasis in adults, active psoriatic arthritis in adults, and active ankylosing spondylitis in adults.
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; may be stored at room temperature (up to 25°C or 77°F) for a maximum of 21 days.
Manufacturer & Packaging
Manufacturer: Janssen Cilag International N.V., BELGIUM
Package Size
1ml PFS
Price & Supplier
Price in UAE: AED 11243.50
Dosage Information
Adult Dose
Initial dose: 100 mg subcutaneously at week 0 and week 4; Maintenance dose: 100 mg subcutaneously every 8 weeks thereafter.
Pediatric Dose
Safety and efficacy not established in pediatric patients under 18 years of age.
Side Effects
Injection site reactions, upper respiratory infections, headache, nausea, and fatigue.
Contraindications & Precautions
Hypersensitivity to guselkumab or any component of the formulation; active infections, including tuberculosis.
Important Warnings
Risk of serious infections; monitor for signs and symptoms of infection; may increase the risk of malignancies; live vaccines should be avoided during treatment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.